Storie by Paul Armentano
October 4, 2014 |
Scientific
revelations are published almost daily in regard to the healing
properties of the cannabis. But most of these findings appear solely in
obscure, peer-reviewed journals and go largely unnoticed by the major
media. Here are five new cannabis-centric studies that warrant
mainstream attention.
Marijuana Use Is Associated With Decreased Mortality In TBI Patients
Traumatic
brain injury (TBI) patients with a history of cannabis use possess
increased survival rates compared to non-users, according data published
this month in the journal American Surgeon. UCLA Medical Center
investigators conducted a three-year retrospective review of brain
trauma patients. Data from 446 separate cases of similarly injured
patients was assessed. Of those patients who tested positive for the
presence of marijuana, 97.6 percent survived surgery. By contrast,
patients who tested negative for the presence of pot prior to surgery
possessed only an 88.5 percent survival rate.
"Previous studies
conducted by other researchers had found certain compounds in marijuana
helped protect the brain in animals after a trauma," the study’s lead
author said in a press release. "This study [is] one of the first in a
clinical setting to specifically associate THC use as an independent
predictor of survival after traumatic brain injury."
CBG Administration Halts Cancer Progression
The
administration of the nonpsychotropic plant cannabinoid cannabigerol
(CBG) possesses potent anti-colon cancer activities and inhibits
cancerous tumor growth, according to data published in September in the
journal Carcinogenesis. A team of Italian researchers at the University
of Naples assessed the effects of CBG on colon tumorigenesis.
Investigators reported that the compound promoted apoptosis (cancer cell
death) and reduced cell growth in colorectal cancer cells. CBG dosing
also inhibited colorectal tumor growth in animals. Authors concluded:
“CBG hampers colon cancer progression in vivo and selectively inhibits
the growth of colorectal cancer cells. … CBG should be considered
translationally in colorectal cancer prevention and cure.”
Parkinson’s Patients Respond Favorably to Cannabis Therapy
Patients
with Parkison’s disease report significant improvement following
cannabinoid therapy. Writing in September in the Journal of
Psychopharmacology, investigators at the University of São Paulo in
Brazil reported on the efficacy of the plant cannabinoid cannabidiol
(CBD) versus placebo in 21 subjects with Parkinson's. Authors reported
that the administration of 300 mg doses of CBD per day was associated
with "significantly different mean total scores" in subjects' well-being
and quality of life compared to placebo.
The Brazilian study is
the second paper in recent months specific to the potential healing
effects of cannabinoids in PD patients. In April, researchers at Tel
Aviv University in Israel reported that the inhalation of whole-plant
improves various symptoms of PD in a cohort of 22 subjects. Marijuana
use was associated with "significant improvement after treatment in
tremor, rigidity, and bradykinsea (slowness of movement),” authors
reported in the journal Clinical Neuropharmacology. They added: “There
was also significant improvement of sleep and pain scores. No
significant adverse effects of the drug were observed."
Marijuana Use Mitigates Symptoms of Opiate Withdrawal
Cannabis
consumption is associated with reduced symptoms of opiate withdrawal in
subjects undergoing methadone maintenance treatment, according to
recent findings published in The American Journal on Addictions.
Investigators at the Farber Institute for Neurosciences at Thomas
Jefferson University in Philadelphia assessed the use of cannabis in 91
opiate-dependent subjects undergoing methadone maintenance treatment.
Authors reported that subjects' pot use during treatment was associated
with less severe symptoms of withdrawal on the clinical opiate
withdrawal scale (COWS), an index designed to serve as an objective
measure of opiate withdrawal. "[I]ncreased cannabis use was found to be
associated with lower severity of [opiate] withdrawal in a subset of the
sample with available chart data," authors concluded. "These results
suggested a potential role for cannabis in the reduction of withdrawal
severity during methadone induction."
Inhaled Cannabis Facilitates Disease Remission In Patients With Crohn’s Disease
Inhaling
cannabis reduces symptoms of Crohn's disease compared to placebo in
patients who have not been responsive to conventional pharmaceutical
therapies, according to clinical trial data published recently in the
journal Clinical Gastroenterology and Hepatology. Researchers at the
Meir Medical Center, Department of Gastroenterology and Hepatology in
Israel assessed the safety and efficacy of inhaled cannabis versus
placebo over a period of eight weeks in 21 subjects with
treatment-resistant Crohn's disease. Investigators reported, "Our data
show that 8-weeks treatment with THC-rich cannabis, but not placebo, was
associated with a significant decrease of 100 points in CDAI (Crohn's
Disease and activity index) scores." Five of the eleven patients in the
study group also reported achieving disease remission (defined as a
reduction in patient's CDAI score by more than 150 points). Overall,
inhaled cannabis treatment was associated with “no significant side
effects.”
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