Blood test can detect Alzheimer’s neurodegeneration biomarker in blood: Pitt Study

 

https://www.the-sun.com/health/7012310/blood-test-detect-alzheimers-stopping-illness/

 https://www.upmc.com/media/news/122722-alzheimers-neurodegeneration

 https://www.sciencedaily.com/releases/2022/12/221228092244.htm

A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer’s disease neurodegeneration in a blood sample. The biomarker, called “brain-derived tau,” or BD-tau, outperforms current blood diagnostic tests used to detect Alzheimer’s-related neurodegeneration clinically. Current blood diagnostic methods can accurately detect abnormalities in plasma amyloid beta and the phosphorylated form of tau, hitting two of the three necessary checkmarks to confidently diagnose Alzheimer’s. But the biggest hurdle in applying the AT(N) Framework to blood samples lies in the difficulty of detecting markers of neurodegeneration that are specific to the brain and aren’t influenced by potentially misleading contaminants produced elsewhere in the body.