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| What Did They Find?
The first vaccine that was tested was the Infanrix Hexa vaccine. It’s
a six-in-one vaccine that’s manufactured by GlaxoSmithKline (GSK)
that’s supposed to contain the following antigens: tetanus, diphtheria,
and pertussis toxoids; inactivated poliomyelitis viral strains 1-2-3;
and hepatitis B surface antigen.
Corvelva discovered that none of these antigens were actually in the
vaccine, which means it had zero antibodies to the intended antigens to
be created. This was a huge shock, and in addition to that they also
found the following:
Traces of 65 chemical cross-contaminants from other manufacturing lines:
- chemical toxins;
- unrecognizable macromolecules;
- various free bacterial peptides that are potential allergens and are capable of inducing autoimmune reactions.
According to Corvelva,
Tetanus, diphtheria and pertussis toxoids, D antigens of
Poliomyelitis 1-2-3, hepatitis B proteins obtained with genetic
engineering and Haemophylus polysaccharides chemically linked to tetanus
toxoid as carrier. Toxoids are created by treatments with formaldehyde
and glutaraldehyde that should remove toxicity keeping intact their
ability to stimulate protective antibodies against original toxins.
We were expecting to find the three toxoids and the other antigens
not modified by treatment with formaldehyde and glutaraldehyde, to
separate the antigens from each other and to be digestible by the enzyme
specific for proteins (trypsin). We have found instead a real
polymer, insoluble and indigestible, that we supposed to be the set of
antigens chemically bound together (has to be defined if this is present
as an aggregate of the individual antigens or a single macromolecule),
on which we can find in literature partial information regarding the
single antigens.
This macromolecule could not be recognized in any way by the
protein databases, and in fact it turned out to be a solid compound of
an unknown chemical structure.
Proteins solubility and their digestion (i.e. the capacity to divide
them into small peptide fragments) are two typical proteins
characteristics that not only makes it possible to study them through
some specific analysis methods but are also fundamental for the interaction with the immune system to create protective antibodies,
because if the protein structure is heavily altered from the original
one, the new antibodies result completely different from those that are
able to attack the original antibodies causing illnesses.
Since this polymer we have encountered, derived from the antigenic
mix, is not only different for its spatial conformation but it’s
chemically different, so we can state that we are not facing
antigens similar to the original ones but in the form of a compound with
an unknown and unpredictable toxicity and efficacy.
The fact that the vaccine antigens were not detected is seriously
concerning, and so is the fact that, of the 65 signs of chemical
contaminants, only 35% are known. This was only the first phase of this safety testing, as a second analytical study with standard controls will be released.
Read More Here
Download: CORVELVA-Study-on-the-chemical-composition-profile-of-Infanrix-Hexa.pdf |
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